磁共振成像门静脉造影血流动力学改变在预测恶性肝病预后的作用

MRI portal vein hemodynamic changes in predicting malignant liver disease prognosis effect

目的分析磁共振成像(MRI)门静脉造影血流动力学改变在预测恶性肝病预后中的应用价值。方法选取于2011年9月至2013年9月在我院治疗的肝硬化门静脉高压患者59例作为观察组,取同期入院体检健康者30名作为对照组,分析2组患者MRI门静脉造影血流动力学改变情况。结果观察组的血管内径、血流量参数较对照组低,平均血流速度较对照组,差异均具有统计学意义(P<0.05)。对比分析不同Child-Pugh分级患者的恶性肝病,A级患者血管内明显高于B级、C级,平均血流速度低于B级、C级,差异均具有统计学意义(P<0.05)。3组患者血流量参数的变化情况,组间差异具有统计学意义(P>0.05)。结论加强MRI门静脉造影血液动力学改变在恶性肝病预测中的应用,能够了解患者疾病发展情况,对临床确定治疗方案具有较高的应用价值。

Objective To analyze the MRI portal vein hemodynamic changes in the predictive value of prognosis of malignant liver disease. Methods From 2011 september to 2013 september in our hospital treatment of liver cirrhosis with portal high in 59 cases as the observation group, the hospitalized 30 healthy subjects as control group, of two groups of patients with MRI portal vein hemodynamie changes. Results The blood flow parameters of the observation group was lower than that in control group, the blood vessel diameter, mean flow velocity compared with the control group, the differences were statistically significant（P〈0.05）. Comparative analysis of different Child-Pugh clas- sification of malignant fiver disease patients, vascular patients was significantly higher than that of B grade, Grade A in C, the mean blood flow velocity below the B level, C level, the differences were statistically significant（P〈0.05）. Changes of blood flow parameters in three groups, with statistically significant difference between groups （P〉0.05）. Conelusion MRI portal vein hemodynamic changes in malignant liver disease prediction, to understand the disease situation, determine the treatment scheme has high application value in clinical.