^(131)I治疗甲亢后早发甲低临床效果评估

Evaluation and Analysis on the Clinical Effect of Early Hypothyroidism After ^(131)I Therapy for Hyperthyroidism

目的分析131I治疗甲亢后早发甲低临床效果评估。方法将收治于我院的131I治疗甲亢患者213例为研究对象,治疗后对患者进行随访,根据患者是否发生甲低将其分成非甲低组以及甲低组,对两组患者治疗前后甲状腺功能、131I剂量、甲状腺组织摄取量、以及内科药物治疗等因素与甲低之间的关系进行分析。结果在使用131I的剂量上两组患者并无差异(P>0.05),但是每克摄取剂量间存在显著差异(P<0.05)。结论患者每克摄取131I量与治疗甲亢时继发甲低之间关系密切,因此在临床用药时可以对131I的给药量进行调整来降低和防止早发甲低的情况发生。

Objective To analyze and evaluate the clinical effect of early hypothyroidism after 131I therapy for hyperthyroidism. Methods 213 patients of hyperthyroidism were treated in our hospital as the research object, after treatment of patients were followed up, according to whether patients with hypothyroidism are divided into non hypothyroidism group and CH group, relationship between thyroid function and the dose of radioiodine, thyroid tissue uptake, and medical treatment and hypothyroidism before and after the treatment, the patients in the two groups analysis. Results There was no difference between the two groups at the dose of 131I （P〈0.05）, but there was a significant difference between the dose per gram （P〈0.05）. Conclusion Patients per gram of 131I uptake amount and the treatment of hyperthyroidism secondary hypothyroidism between closely related, so in the clinical medication can of 131I dose adjusted to reduce and prevent the occurrence of hypothyroidism.