脑利钠肽与组织多普勒在诊断老年无症状心力衰竭患者中的应用与评价

Doppler in the Diagnosis in Elderly Patients With Asymptomatic Heart Failure

目的研究脑利钠肽与组织多普勒成像技术在老年无症状心力衰竭中的应用价值。方法选取老年无症状心力衰竭患者124例,按脑利钠肽水平分为脑利钠肽正常组、脑利钠肽异常组,将50例有症状的心力衰竭作为对照组,比较三组间组织多普勒的差异。结果脑利钠肽正常组、脑利钠肽异常组、对照组平均Sm依次降低,但是在脑利钠肽正常组、脑利钠肽异常组间比较,P>0.05,两组与对照组比较,均P<0.05;二尖瓣E/Em依次增大,三组之间比较,P<0.05。结论无症状心力衰竭BNP异常组与BNP正常组比较舒张功能障碍程度更为严重,其原因可能为早期舒张性心力衰竭,因此BNP在早期诊断舒张性心衰具有一定临床意义。二尖瓣E/Em比值可有效地反映心力衰竭患者的左心室舒张末充盈压。

Objective To study the brain natriuretic peptide and tissue Doppler imaging technology in the application value of senile asymptomatic heart failure. Methods 124 cases of elderly patients with asymptomatic heart failure by brain natriuretic peptide levels were divided into normal group of brain natriuretic peptide and brain natriuretic peptide abnormal group, will be as a control group of 50 cases of symptomatic heart failure, comparison of tissue Doppler difference between three groups. Results The result of brain natriuretic peptide of normal and abnormal brain natriuretic peptide group, control group, in turn, reduced the average Sm, but in brain natriuretic peptide between normal and abnormal brain natriuretic peptide 〈br〉 group comparison P〉0.05, both group compared with control group, P〈0.05, Mitral E/Em, in turn, increases, comparison between three groups P〉0.05. Conclusion Asymptomatic heart failure group BNP abnormal diastolic dysfunction degree than normal group, the BNP may be early diastolic heart failure, BNP on diastolic heart failure early diagnosis is of certain clinical significance. Mitral E/Em ratio can effectively reflect the heart failure in patients with left ventricular end-diastolic pressure.