通心络对单纯颈动脉斑块患者血浆超敏C反应蛋白和脂蛋白相关磷脂酶A2的影响

Tongxinluo in Patients With Pure Carotid Plaques Hypersensitive C-reactive Protein and Plasma Lipoprotein Associated Phospholipase A2

目的探讨通心络对单纯颈动脉斑块患者血浆超敏C反应蛋白和脂蛋白相关磷脂酶A2的影响。方法选取单纯颈动脉粥样硬化患者112例作为通心络治疗组,同时选取正常的体检健康人群43例作为对照组,治疗3个月后,比较两组治疗前后hs-CRP、Lp-PLA2水平。结果通心络组治疗前后hs-CRP、Lp-PLA2与正常对照组对比均有显著性差异(P<0.01)。结论 Lp-PLA2与hs-CRP可以较好地评价动脉粥样硬化的炎性血清学指标,特别是Lp-PLA2水平的检测可以更好的识别患有动脉粥样硬化的高危个体,同时通心络具有可靠的抗炎作用。

Objective To investigate Tongxinluo simple carotid plaque plasma high-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2. Methods Chose 112 patients with simple carotid atherosclerosis as tongxinluo treatment group, and select normal physical healthy crowd 43 cases as control group, 3 months after treatment, compared two groups before and after treatment the hs CRP, Lp PLA2 level. 〈br〉 Results Tongxinluo group before and after treatment the hs CRP, Lp PLA2 compared with normal control group had significant difference （P〈 0.01）. Conclusion Lp-PLA2 and hs-CRP can be better evaluated atherosclerosis inflammatory serum markers, particularly the detection of Lp-PLA2 levels can better identify with atherosclerosis in high-risk individuals, while passing Tongxinluo has a reliably anti-inflammatory effect.