甲睾酮联合米非司酮治疗高龄子宫肌瘤患者的疗效分析

Analysis of Therapeutic Effect of Methyltestosterone and Mifepristone Treatment of Elderly Patients with Myoma of Uterus

目的:研究甲睾酮联合米非司酮治疗高龄子宫肌瘤患者的疗效。方法:本次研究选择2013年9月-2014年11月在笔者所在医院接受治疗的高龄子宫肌瘤患者70例。按入院先后顺序,将患者分为观察组和对照组各35例。对照组口服米非司酮治疗,观察组在此基础上服用甲睾酮治疗,治疗2个疗程,每疗程3个月,比较两组患者的治疗效果。结果:两组患者治疗后的子宫体积和肌瘤的体积均小于治疗前,差异均有统计学的意义(P<0.05),表示两组都可以缩瘤;且观察组患者的子宫体积及肌瘤体积均明显小于对照组,差异均有统计学的意义(P<0.05)。且观察组患者的治疗有效率为97.1%,明显高于对照组患者的80.0%,差异有统计学意义(P<0.05)。结论:甲睾酮和米非司酮联合治疗高龄子宫肌瘤患者能起到很好效果,可以帮助子宫肌瘤缩小,改善患者的症状。

Objective： To study the efficacy of mifepristone combined with methyltestosterone elderly patients with uterine fibroids.Method： 70 eases of elderly patients with uterine fibroids were selected in our hospital from September 2013 to November 2014.According to the order of admission, patients were divided into the observation group and the control group, 35 cases in each group.The control group was treated with mifepristone treatment, observation group was taken a testosterone treatment on this basis, two courses, each course of three months, the therapeutic effect of two groups were compared.Result： After treatment, two groups of patients＇uterine fibroid volume and uterine volume were less than before, the differences were significant, with statistical significance（P〈0.05）, saidthat both groups can shrink tumors ; uterine volume and range of patients in the observation group fibroid volume were lower than in the control group of patients, the differences were statistically significance（P〈0.05）.And the effective treatment of patients in the observation group was 97.1%, significantly higher than 80.0% of the patients treatment efficiency, the differences were statistically significant（P〈0.05）.Conelusion： Methyhestosterone and mifepristone treatment of elderly patients with uterine fibroids can take a good effect, can help shrink fibroids and improve the patient＇s symptoms.