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冠状动脉慢血流患者脉搏波传导速度的变化 被引量:4

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摘要 目的研究冠状动脉慢血流(coronary slow flow,CSF)现象与臂踝脉搏波传导速度(brachial-ankle pulse wave velocity,ba PWV)的相关关系。方法选择64例因胸痛入住福建医科大学附属第二医院拟诊为冠心病并行冠状动脉造影(CAG)显示心外膜主要冠状动脉无明显病变的病例。根据校正的TIMI血流计帧法(c TFC)计算各支冠状动脉的TIMI帧数。冠状动脉平均帧数大于27帧定义为CSF,将患者分为CSF组(n=28例)和正常血流(NCF)对照组(n=36例)。应用t检验和卡方检验比较两组患者各项临床资料的差异,并采用二分类Logistic回归分析法对相关因素进行分析。结果两组患者中年龄、性别、高血压、糖尿病、吸烟史、血脂水平、空腹血糖水平、血浆纤维蛋白原的水平差异均无统计学意义,而CSF组的ba PWV及ba PWV%均显著高于NCF组(1746.29±342.51)vs(1516.99±269.47)cm/s,(P<0.01);(26.13±19.09)vs(12.29±19.23),(P<0.01)。二分类Logistic回归分析表明ba PWV和性别是影响CSF的危险因素(OR=8.40、9.69)。结论 CSF组ba PWV水平升高,提示CSF存在冠状动脉粥样硬化。性别(男性)和升高的ba PWV是CSF发生的危险因素,ba PWV可用于CSF高危人群的筛查。
出处 《心脑血管病防治》 2015年第4期293-295,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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参考文献11

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