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依折麦布在动脉粥样硬化性心血管疾病中的应用评价 被引量：2

Comment on application of ezetimibe in the atherosclerotic cardiovascular disease
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摘要 动脉粥样硬化性心血管疾病(ASCVD)是危害人类健康的主要疾病,在强化他汀治疗后,虽可显著降低心血管风险,但是仍存在其他风险。近年来,有关依折麦布与他汀类药物联用治疗ASCVD的研究,证实了EZ作为非他汀药物,可降低LDL-C水平,减少心血管事件,并确认了EZ的安全性。本文对此进行综述。 Atherosclerotic cardiovascular disease （ASCVD） is the main disease to harm the health of human. Although intensive therapy of statins can significantly reduce the cardiovascular risk in ASCVD patients, but there are still a lot of residual risks. In recent years, a series of clinical trials about the combination of EZ and statins have confirmed that EZ can lower the level of LDL-C and reduce cardiovascular events with good safety. The articles review the related clinical trials.
作者 宁文娜 张大庆 赵琳
机构地区 中国医科大学附属盛京医院 中国医科大学药学院
出处 《实用药物与临床》 CAS 2015年第8期981-985,共5页 Practical Pharmacy and Clinical Remedies
关键词 依折麦布 他汀类药物 胆固醇 动脉粥样斑块 心脑血管终点事件 EZ Statins Cholesterol Arterial atheromatous plaque Cardiovascular endpoint events
分类号 R54 [医药卫生—心血管疾病]
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参考文献26

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二级参考文献43

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共引文献37

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实用药物与临床
2015年 第8期

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