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易感基因多态性与肠易激综合征 被引量:2

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摘要 肠易激综合症(IBS)由多因素综合致病,其发病机制尚不明确,与遗传因素、肠道功能失调、内脏高敏感性、精神因素及脑-肠轴互动等有关。目前遗传因素成为国内外研究的热点,主要有神经递质机制、炎性反应相关机制、离子通道机制及胆汁酸代谢机制。了解IBS分子水平的发病机制,对诊断性生物标志物及药物的研发意义重大。
作者 成璇 吴战军
出处 《国际消化病杂志》 CAS 2015年第3期177-179,共3页 International Journal of Digestive Diseases
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