子宫内膜癌淋巴结切除的必要性

Necessity of lymphadenectomy for endometrial cancer patients

淋巴转移是影响子宫内膜癌患者预后的主要因素,而早期子宫内膜癌患者发生淋巴转移几率极低,因而对早期子宫内膜癌患者是否常规实施淋巴结切除术及淋巴切除范围一直存在争议.本文拟从淋巴切除术对早期内膜癌患者预后的影响阐述淋巴切除术的适用范围,分析内膜癌患者淋巴转移的高危因素,探讨其在内膜癌手术中的价值,并进一步探讨前哨淋巴结对子宫内膜癌手术分期及预后判断的指导作用,明确早期子宫内膜癌患者行淋巴切除术的条件及范围.

Lymph node metastasis is the main prognostic factor of endometrial cancer patients.As the metastasis of early endometrial cancer patients is very low,it remains a controversy whether these patients are necessary to undergo conventional lymphadenectomy and a challenge to confirm the scope of lymph node dissection.We intend to demonstrate the application of lymphadenectomy in patients with early endometrial cancer via the impact of lymphadenectomy on the prognosis of these patients.The risk factors for lymph node metastasis of endometrial cancers were analyzed to explore its value in the surgical option.Furthermore,the guidance of sentinel lymph node in surgical staging and prognostic prediction of early endometrial cancer was explored to clarify the applied condition and scope of lymphadenectomy in these patients.