基于国际专利分类法的上海中药产业创新技术热点分析

Analysis on Hot Spots of Innovative Technology of Chinese Medicine Industry in Shanghai Based on The IPC Classification of Patents

目的分析近年来我国上海地区中药产业创新技术研究热点。方法采用国际专利分类法(IPC)分类号结合关键词组合检索《国家知识产权局专利数据库》,对2002-2013年所公开的上海地区中药相关专利的IPC分类号进行统计分析。结果中药制剂的治疗活性热点分布:中药开发的最主要活性是抗肿瘤,其后依次为治疗局部缺血或动脉粥样硬化疾病及高血糖、高血脂等心脑血管系统疾病的活性,治疗消化道或消化系统疾病的活性,抗感染、抗病毒、抗菌、抗炎等活性。剂型研究热点分布:中药新剂型研究主要体现在传统剂型改进和新剂型开发,胶囊剂、片剂、口服液、注射剂等是研究较多的新剂型。药用来源分布:药用动植物主要来源于"被子植物亚门",药用动物较少,主要是昆虫类。结论近年来我国上海地区的中药产业创新技术研究热点主要分布在肿瘤、心脑血管系统疾病、消化系统疾病等的治疗药物上,新剂型研究热点主要在传统剂型改进和新剂型开发,"被子植物亚门"的药用植物为开发重点。

Objective To analysis the hot spots of innovative technology of Chinese medicine industry in Shanghai during the recent years.Methods Patent Database of State Intelletual Property Office was retrieved by IPC class numbers combined with keywords and the IPC classification of the Chinese medicine patents in Shanghai area during 2002-2013 were under statistical analysis.Results The hot spot distribution of therapeutic activity of TCM preparations：Antineoplastic is the most important activity of Chinese medicine development, followed by the activities of treatment of inadequate blood flow or cardiovascular system diseases, such as hyperglycemia, high cholesterol, and so on. The activity of treatment of the digestive tract or digestive system diseases, followed by the activities of anti infection, antiviral, antibacterial, anti-inflammatory treatment, etc. The hot spot distribution of dosage：Researches on new dosage of Chinese medicine were mainly reflected in the improvement of traditional dosage form and development of new formulations. The capsules, tablets, oral liquid, and injections were the new dosage forms under the most researches. The distribution of medical resources：Medicinal plants or animals mainly came from “angiosperm”. Medicinal animals were less than medicinal plants, which mainly belonged to insecta.ConclusionThe hot spots of innovative technology of Chinese medicine industry in Shanghai are mainly distributed in the medicine of anti-tumor, cardiocerebral vascular diseases, digestive system diseases and so on in recent years. The researches of new formulation focus on the traditional dosage form improvement and new formulations development. “Angiosperm” is the key to the development of medicinal plants.