不同位置胸腔胃在食管癌术后放疗中的剂量分析

Dose Analysis of Different Position Intrathoracic Stomach in the Postoperative Radiotherapy of Patients with Esophageal Carcinoma

目的评价食管癌术后放疗中不同位置胸腔胃的受照剂量。方法收集15例不同位置胸腔胃患者,其中左侧、右侧、纵隔胸腔胃患者各5例,利用治疗计划系统设计放疗计划,利用剂量体积直方图比较分析胸腔胃接受的平均剂量(Dmean)、接受5 Gy、25 Gy、40 Gy、50 Gy照射的靶体积百分比(V5、V25、V40、V50)。结果纵隔胸腔胃的Dmean、V5、V25、V40、V50明显高于左侧、右侧(P<0.05);左侧、右侧胸腔胃的Dmean、V5、V25、V40、V50比较差异均无统计学意义(P均>0.05)。结论纵隔胸腔胃较左侧、右侧受照剂量较大,放射性胃损伤发生风险可能高。

Objective To evaluate the dose of different position intrathoracic stomach in the postoperative radio- therapy of patients with esophageal carcinoma. Methods Fifteen patients with different position intrathoracic stom- ach （the left intrathoracic stomach 5 patients, the right intrathoracic stomach 5 patients and the mediastinal intratho- racic stomach 5 patients） were collected. The radiotherapy plan was did by using the radiotherapy planning system, and the dose volume histogram was used to compare the Dmean and V5 , V25, V40, V50 of the intrathoracic stomach. Re- suits The Dmean and V5 ,V25 ,V40 ,V50 of the mediastinal intrathoracic stomach were significantly higher than those of the left intrathoracic stomach and the fight intrathoracic stomach （ P 〈 0.05 ） ; there was no statistical difference in the Dmean and V5 , V25, V40, V50 between the left intrathoracic stomach and the right intrathoraeic stomach （ P 〉 0. 05 ）. Conclusion The dose of the mediastinal intrathoracic stomach was higher than those of the left intrathorac- ic stomach and the right intrathoracic stomach,the radioactive stomach injury occurrence probability may be high.