人工皮(亲水性敷料)与红霉素软膏治疗新生儿皮肤损伤效果比较

Comparison of the effects of artificial skin(hydrophilic dressing) and erythromycin ointment in the treatment of neonatal skin injury

目的通过探讨人工皮（亲水性敷料）与红霉素软膏治疗新生儿皮肤损伤的疗效,旨在为临床快速促进新生儿皮肤损伤恢复并提高治疗效率提供理论依据。方法选择2014年3月~2015年3月在我院接受治疗的新生儿皮肤损伤160例,随机平均分成研究组和对照组两组,对照组患儿给予红霉素软膏治疗,研究组患儿给予人工皮（亲水性敷料）进行治疗,对比两组患儿伤口愈合时间、平均换药次数、并发症发生率、未愈率及治疗有效率。结果研究组患儿伤口愈合时间（4.47±0.76）d、平均换药次数（3.18±0.52）次、并发症发生率5.00%、未愈率3.75%、治疗有效率95.00%,研究组均显著优于对照组,差异有统计学意义（P〈0.05）。结论人工皮（亲水性敷料）在治疗新生儿皮肤损伤时可快速促进伤口愈合、减少换药次数并提高治疗有效率。

Objective To explore the curative effects of artificial skin（hydrocolloid dressing） and erythromycin ointment in the treatment of neonatal skin injury, and to provide theoretical evidences for the promotion of clinically rapid recov- ery of neonatal skin injury and the improvement of curative effects. Methods A total of 160 patients with neonatal skin injury who were treated in our hospital from March 2014 to March 2015 were selected. They were randomly and aver- agely assigned to two groups, research group and control group. Infant patients in the control group were given the treatment of erythromycin ointment, and infant patients in the research group were given the treatment of artificial skin （hydrophilic dressing）. Wound healing time, average frequency of dressing change, incidence of complications, non-cure rate and effective rate of treatment were compared between the two groups of infant patients. Results In infant patients of the research group, wound healing time was （4.47±0.76） d, average frequency of dressing change was （3.18±0.52） times, incidence of complications was 5.00%, non-cure rate was 3.75% and effective rate of treatment was 95.00%. All in- dices in the research group were significantly better than those in the control group, and the differences were statisti- cally significant （P〈0.05）. Conclusion Artificial skin （hydrophilie dressing） in the treatment of neonatal skin injury is able to promote the wound healing rapidly, can reduce of treatment. the frequency of dressing change and improve the effective rate