我院248例药物不良反应报告分析

Analysis on reports of 248 cases of adverse drug reactions in our hospital

目的分析我院药物引起的不良反应（ADR）,探讨其特点及影响因素。方法对2012~2014年间我院收集的248例不良反应（ADR）报告进行统计、分析。结果 248例ADR报告中,涉及药品共12类97种,其中抗感染药物列居首位,以静脉滴注的给药方式为主要途径。累及皮肤及其附件的比例最大,其次为消化系统。结论引发药物ADR的因素多样,临床应重视和加强ADR监测和上报工作,以减少或避免ADR的发生。

Objective To analyze adverse reactions induced by drugs （ADR） in our hospital, and to explore their charac- teristics and influencing factors. Methods A total of 248 cases of reported ADR from 2012 to 2014 were collected and analyzed in our hospital. Results Among 248 cases of ADR reports, involved drug products were 97 types in 12 classes, in which anti-infective drug was ranked the first. The main administration route was intravenous drip. The proportion of affected skins and their attachments was the biggest, followed by the digestive system. Conclusion Factors inducing ADR are multiple. ADR monitoring and reporting works should be focused and strengthened clinically, so as to reduce or avoid ADR.