摘要
IgG4相关性疾病是一种由免疫介导的累及多器官或组织的慢性自身炎症性系统性疾病,其特征为血清IgG4升高、组织中大量IgG4阳性浆细胞浸润、多灶性纤维硬化性改变及闭塞性静脉炎。目前其临床谱逐渐扩大,且对激素敏感。该病临床症状异质,故诊断困难,易误诊或漏诊,近些年逐渐被大家所认知。本文就近年来IgG4-RD的流行病学、发病机制、临床表现、诊断、鉴别诊断及治疗等方面的最新研究进展进行综述,以加强我们临床医生对该病的认识。
IgG4-RD is a kind of chronic and systemic disease which is characterized by elevatedserum IgG4 level, abundant IgG4-positive plasma cell infiltration in the involved organs,storiform fibrosis and obliterative phlebitis. IgG4-RD responses well to corticosteroid treatment. Its complicated clinical manifestation and multidiscipline involve- ment make it easy to be misdiagnosed or misdiagnosed. In order to better understand this disease,in this article,we will review relevant literatures of this disorder.
出处
《中国现代医生》
2015年第16期152-156,共5页
China Modern Doctor
