慢性阻塞性肺疾病合并抑郁症状相关因素及干预措施

Relevant factors and intervention measures of chronic obstructive pulmonary disease associated with depressive symptoms

目的探讨慢性阻塞性肺疾病(COPD)合并抑郁症状的相关因素及干预措施。方法选择220例慢性阻塞性肺疾病患者作为研究对象,统计抑郁症状的发生率,比较抑郁症状组与无抑郁症状组患者年龄、性别、文化水平、婚姻、经济状况、日常生活自理水平、认知功能、家庭支持、肺功能、慢性阻塞性肺疾病病程、医疗费用等因素上的差异。结果 220例慢性阻塞性肺疾病患者合并抑郁症状70例(31.82%),其中轻度抑郁症状40例(57.14%)、中度20例(28.57%)、严重10例(14.29%),单因素检验两组患者的年龄、性别、文化水平、婚姻、经济状况、日常生活自理水平、认知功能、家庭支持、肺功能、慢性阻塞性肺疾病病程、医疗费用,差异均有统计学意义(P<0.05);Logistic回归分析引起慢性阻塞性肺疾病抑郁症状的危险因素:年龄大(OR=4.62)、文化程度低(OR=3.97)、家庭支持缺少(OR=3.42)、FEV1实测值/预计值低(OR=2.90)。结论慢性阻塞性肺疾病抑郁症状发生率高,影响因素多种多样,应实施相应的干预措施以减少慢性阻塞性肺疾病抑郁症状的发生。

Objective To investigate relevant factors and intervention measures of chronic obstructive pulmonary dis ease （COPD） associated with depressive symptoms. Methods A total of 220 patients with COPD were selected as the study subjects and the incidence of depressive symptoms was calculated. The depressive symptom group and the non-depres- sive symptom group were compared by age, sex, educational level, marital status, economic status, self-independent level of daily living, cognitive function, family support, lung function, course of COPD, medical expense and other factors. Results Of the 220 patients with COPD, 70 patients were associated with depressive symptoms （31.82%, 70/220）, includ- ing 40 patients with mild depressive symptoms （57.14%）, 20 moderate （28.57%） and 10 severe （14.29%,）. Single factor analysis showed that the two groups of patients were significantly different in age, sex, educational level, marital status, economic status, self-independent level of daily living, cognitive function, family support, lung function, course of COPD and medical expense （P〈0.05）. Logistic regression analysis found the risk factors of COPD depressive symptoms as fol- lows： older age （OR=4.62）, lower educational level （OR=3.97）, lack of family support （OR=3.42） and lower measured value/estimated value of FEV1 （OR=2.90）. Conclusion The incidence of COPD depressive symptoms is high and there are various influencing factors, and therefore corresponding intervention measures should be implemented in order to re- duce the occurrence of COPD depressive symptoms;