胃印戒细胞癌临床病理分析及内镜特点

CLINICOPATHOLOGICAL AND ENDOSCOPIC FEATURES OF GASTRIC SIGNET RING CELL CARCINOMA

目的探讨胃癌中印戒细胞癌的临床病理特征及内镜特点。方法回顾性分析2012年1月—2015年1月经雅安市人民医院手术病理证实的胃癌中21例印戒细胞癌和220例非印戒细胞癌患者的临床资料。结果胃癌中,印戒细胞癌与非印戒细胞癌在年龄、性别、肿瘤发生部位、侵犯神经上差异有统计学意义(P<0.05),而在肿瘤直径、浸润深度、淋巴结转移、远处转移、内镜特点上差异无统计学意义(P>0.05)。结论胃癌中的印戒细胞癌好发于年轻人、女性及胃窦部,容易侵犯神经,内镜下缺乏特异性表现,且CEA、CA724、CA199无特异性增高。

Objective To investigate the clinicopathologic and endoscopic characteristics of signet ring cell carcinoma. Methods Retrospective study on the clinical data of 21 cases diagnosed with gastric signet ring cell carcinoma and 220 patients with nonsignet ring cell carcinoma who received surgical resection and pathologically confirmed from January 2012 to January 2015 in Ya＇an People＇s Hospital. Results Significant differences were noted in age, gender, tumor location and neural invasion between patients with signet ring cell carcinoma and non- signet ring cell carcinoma （P〈0.05）, while there were no differences in tumor size, depth of tumor invasion, lymph node metastasis, distant metastasis and endoscopic features （P〉0. 05）. Conclusions The gastric signet ring cell carcinoma is more associated with young people, female and antrum, easy to violations nerve, endoscopic lack of specific performance, and the CEA, CA724, CA199 no specificity increased.