迷迭香酸的提取纯化及生物活性研究进展

Research Progress on Extraction,Purification and Biological Activities of Rosmarinic Acid

迷迭香酸作为强抗氧化剂,具有抗菌、抗炎、抗病毒、抗肿瘤等多种生物活性。介绍了迷迭香酸的提取及纯化方法,重点讨论了其在抗菌抗病毒、抗氧化及清除自由基、抗炎及免疫调节、保护神经系统、抗辐射抗肿瘤、抑制黄嘌呤氧化酶和保护肝脏与肺等多方面的生物活性,旨在为其规模化制备和应用提供依据。

Rosmarinic acid as a very strong antioxidants exists in rosemary with a high content. It has various biological activities such as anti-biotic, anti-inflammatory, anti-virus and anti-cancer activities. In order to offer more information for large-scale preparation and application, a brief review is presented on the extraction, purification methods. The biological activities of rosmarinic acid, such as antibiosis, antivirus, anti-oxidation , radical-scavenging, anti-inflammatory, immunoregulatian, protecting nervous system, anti-radiation, antitumor, inhibition of xanthine oxidase and protection of livers and lungs are particularly discussed.