微创小梁切除结合生物羊膜移植术治疗青光眼的疗效观察

Effective observation on minimally invasive trabeculectomy combined with biological amniotic membrane transplantation in treatment of glaucoma

目的观察微创小梁切除结合生物羊膜移植术治疗青光眼的临床疗效。方法选取2012年1月至2014年1月该院眼科收治的青光眼患者100例(120眼),将其分为观察组及对照组,观察组实施微创小梁切除结合生物羊膜移植术治疗,对照组仅实施微创小梁切除术治疗,比较2组患者的临床治疗效果。结果经过1年随访,对照组中保持功能性滤过泡40只眼,百分比为66.67%,观察组中保持功能性滤过泡53只眼,百分比为88.33%,差异有统计学意义(P<0.05);治疗后,观察组眼压低于对照组,差异有统计学意义(P<0.05);观察组房水流畅系数高于对照组,差异有统计学意义(P<0.05)。2组患者并发症发生率差异无统计学意义(P>0.05)。结论在青光眼临床治疗中,对患者实施微创小梁切除结合生物羊膜移植术治疗,能够取得良好的临床治疗效果,对眼压起到良好的控制作用,值得推广应用。

Objective To observe the clinical efficacy of minimally invasive trabeculectomy combined with bio logical amniotic membrane transplantation in the treatment of glaucoma. Methods 100 patients（120 eyes） with glau- coma treated in the ophthalmology department of our hospital from January 2012 to January 2014 were selected and divided into the observation group and the control group. The observation group was performed the minimally inva- sive trabeculectomy combined with biological amniotic membrane transplantation,while the control group was imple- mented only minimally invasive trabeculectomy. The clinical curative effects were compared between the two groups. Results After 1-year follow-up,40 eyes in the control group maintained the functional follicle with the percentage of 66.67% ,while 53 eyes maintained the functional follicle with the percentage of 88.33%, the difference was statisti- cally significant （P〈0.05） ;the intraocular pressure after treatment in the observation group was significantly lower than that in the control group,the difference was statistically significant （P〈0.05）, the aqueous outflow facility in the observation group was higher than that in the control group, the difference was statistically significant （P〈0.05）. The occurrence rate of complications had no difference between the two groups（P〉0.05）. Conclusion In the clinical treatment of glaucoma, implementing minimally invasive traheculectomy combined with biological amniotic membrane transplantation can achieve a good clinical effect,better control the intraocular pressure and is worthy of popularization and application.