双氯芬酸钠水分离联合转核技术在超声乳化术中的应用

Application of diclofenac sodium hydrodissection combined with nuclear rotation in phacoemulsification

目的:研究双氯芬酸钠水分离联合转核技术对预防白内障超声乳化术后后发性白内障的影响。方法:将2013-01/2014-12在我院接受白内障超声乳化术的80例86眼患者纳入研究,随机分为两组,观察组患者接受双氯芬酸钠水分离联合转核操作,对照组患者接受平衡液水分离。比较两组患者的后发性白内障程度、视力水平和角膜内皮细胞计数。结果:(1)后发性白内障程度:观察组患者的后发性白内障程度优于对照组(Z=6.982,P<0.05);(2)视力水平:术后1、2、3、4wk时,观察组的患眼视力水平均高于对照组(0.37±0.07 vs 0.23±0.04,0.68±0.09 vs 0.35±0.05,0.77±0.09 vs 0.48±0.06,0.91±0.12 vs 0.68±0.08;F=6.583,8.983,7.182,5.492;P<0.05);(3)角膜内皮细胞计数:术后1、2、3、4wk时,观察组与对照组角膜内皮细胞计数比较,差异无统计学意义(F=1.841,1.003,0.077,0.390;P>0.05)。结论:双氯芬酸钠水分离联合转核技术能有效降低后发性白内障发生率,且眼内使用较为安全。

AIM： To study the effect of diclofenac sodium hydrodissection combined with nuclear rotation on preventing posterior capsular opacification after cataract phacoemulsification. METHODS： Eighty patients （86 eyes） received cataract phacoemulsification in our hospital from January, 2013 to December, 2014 were enrolled and randomly divided into observation group and control group. The patients in observation group were received diclofenac sodium hydrodissection with nuclear rotation, and the patients in control group were received equilibrium liquid hydrodissection. Then degree of posterior capsular opacification, visual acuity and corneal endothelial cells count in two groups were compared. RESULTS： （1） Posterior capsular opacification degree： posterior capsular opacification degree of patients in observation group were better than that of control group （Z=6.982, P〈0.05） ; （2） Visual acuity： at 1, 2, 3 and 4wk after operation, the visual acuity of patients in observation group was higher than that in control group （0.37±0.07 vs0.23±0.04, 0.68±0.09 vs 0.35±0.05, 0.77± 0.09 vs0.48±0.06, 0.91±0.12 vs0.68±0.08; F=6.583, 8. 983, 7.182, 5.492, P〈0.05）. （3） Corneal endothelial cells： at 1, 2, 3 and 4wk after operation, there were no significant difference for corneal endothelial cells count between two groups （F=1.841,1.003, 0.077, 0.390, P〉0.05）. CONCLUSION： Diclofenac sodium hydrodissection combined with nuclear rotation can effectively reduce the incidence of posterior capsular opacification and can be safely used for intraocular treament.