摘要
抗菌肽在医药、食品、农业及水产等领域具有潜在的应用价值,定量构效关系(quantitative structureactivity relationships,QSAR)研究对于指导抗菌肽的优化设计具有重要意义。本文介绍抗菌肽在分子表征及建模等方面取得的研究进展,比较抗菌肽与其他小肽在QSAR研究中的异同,指出其中存在的问题及今后的研究发展方向。
Antimicrobial peptides have potential applications in many fields, such as medicine, food, agriculture, and aquiculture. Quantitative structure-activity relationships （QSAR） research will be helpful for the optimization of antimicrobial peptides. Herein, the recent progress in molecular description and modeling of antimicrobial peptides in comparison to oligo peptides is reviewed. Meanwhile, the existing problems and the future trends are also discussed.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2015年第15期299-304,共6页
Food Science
关键词
抗菌肽
定量构效关系
描述符
氨基酸
数学模型
antimicrobial peptide
quantitative structure-activity relationship
descriptor
amino acid
mathematical model
