急性胰腺炎治疗中生长抑素对胃肠动力的影响

Effect of somatostatin on gastrointestinal motility during the treatment of acute pancreatitis

目的:研究分析临床治疗急性胰腺炎期间生长抑素对胃肠动力的影响。方法:选择在我院住院治疗的94例急性胰腺炎患者,采用计算机随机进行分组,治疗组47例患者在常规治疗的基础上应用生长抑素进行治疗;对照组47例患者应用常规方法治疗。结果:治疗组患者在肛门排气时间、肠鸣音正常时间、血清淀粉酶恢复时间等方面均优于对照组,差异有统计学意义(P<0.05)。结论:生长抑素可有效保护胃肠黏膜,增强胃肠动力,对急性胰腺炎的治疗具有积极的促进作用。

Objective. To study the effect of somatostatin on gastrointestinal motility during the clini cal treatment of acute pancreatitis. Methods： 94 cases of acute pancreatitis patients hospitalized in our hospital were grouped by computer into the treatment group and the control group with 47 cases in each group. The treatment group received somatostatin treatment on the basis of conventional therapy, while the control group was given conventional treatment. Results： Anal exhaust time, the normal bowel sounds, and the recovery time of serum amylase of the patients in the treatment group was significantly superior to those of the control group, which was of statistical difference （P〈0.05）. Conclusion： Somatostatin can effectively protect the gastrointestinal mucosa, enhance the gastrointestinal dynamics. It plays a positive role in the treatment of acute pancreatitis.