社工介入综合干预治疗对精神分裂症患者预后的影响

The Effect of Social Work Comprehensive Intervention on Prognosis of Patients with Schizophrenia

目的:探讨社工介入综合干预治疗对精神分裂症患者预后的影响。方法:采用配对对照的前瞻性研究设计,将400例住院精神分裂症随机分为4种药物(氯丙嗪、舒必利、氯氮平、利培酮)治疗组各100例,每种药物组又随机分为研究组(单纯药物治疗)和对照组(药物加社工介入综合干预)各50例。对各组患者各时段的精神病理症状,出院后的复发率、病情稳定率、个人生活和社会功能完好率进行随访对照分析。结果:治疗8周末各中心研究组和对照组PANSS总分与治疗前比较差异均有统计学意义(P<0.05);组间比较差异亦有统计学意义(P<0.05)。治疗8周末各中心研究组个人和社会功能(PSP)均高于对照组(P<0.05)。治疗6、12、24个月末各中心研究组病情稳定情况均优于对照组,差异有统计学意义(P<0.05或P<0.01)。治疗6、12、24个月末各中心研究组个人和社会功能(PSP)良好率均明显高于对照组,差异有统计学意义(P<0.05或P<0.01)。结论:社工介入综合干预治疗是一种适合我国国情,能改善精神疾病预后较好的综合干预治疗模式。

Objective： To study the effect of social work comprehensive intervention on prognosis of patients with schizophrenia. Method： By using control prospective study design, 400 hospitalized patients with schizophrenia were selected as the research object, and they were randomly divided into 4 kinds of drugs group （ chlorpromazine, sulpiride, elozapine and treatment, each of 100 cases. Each medicine group were randomly assigned to the study group （medicine and social work comprehensive intervention treatment ） and the control group （ simple drug treatment ）, 50 cases in each. Patient＇s mental pathological symptoms, disease recurrence rate after discharge, the stability factor, individual life and social function of pipe in each period were analyze ann compared.Result： Compared with before treatment, the difference of PANSS scores in 8 weekend in each center were statistically significant （ P〈0.05 ） ; 8 weekend, there were statistically significant difference between the study group and the control group in each center （ P〈0.05 ） .Individual and social function （ PSP ） of the study group in each center in 8 weekend were higher than those of the control group （ P〈0.05 ） .Stable condition of the study group in each center after 6, 12, 24 months were better than those of the control group （ P〈0.05 or P〈0.01 ） .Good rate of individual social function （ PSP ） of the study group in each center after 6, 12, 24 months were higher than those of the control group, there were statistically significant difference （ P〈0.05 or P〈0.01 ） . Conclusion： Social work comprehensive intervention treatment is a kind of suitable for China＇s national conditions, it is better comprehensive intervention model to improve the prognosis of mental illness.