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碳纳米管场效应晶体管用于大肠杆菌检测的研究 被引量：1

Detection of escherichia coli using carbon-nanotube field-effect transistor
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摘要 采用连接分子1-芘丁酸琥珀酰亚胺酯(PASE)和大肠杆菌抗体对碳纳米管场效应晶体管(CNTFET)进行修饰,制备出针对大肠杆菌检测的生物传感器。通过扫描电镜发现有连接分子修饰的CNTFET对大肠杆菌有很好的吸附效果,且根据检测大肠杆菌过程中CNTFET源漏电极之间电阻的变化特点,发现仅有连接分子修饰的CNTFET对大肠杆菌有很好的响应效果。另外,用CNTFET检测不同浓度的大肠杆菌时,随着大肠杆菌浓度的增加,源漏电极之间的电阻也越来越大,证明了以CNTFET为基础的生物传感器检测大肠杆菌的可能性。 We the linker and Escherichia coil O157： H7 antibody was used to modify the CNTFET, and the CNT- FET biosensor for Escherichia coli O157：H7 detection was obtained. SEM results showed that CNTFET modified by linker had good adsorption effect on Escherichia coli O157：H7. According to the change of resistance between the electrodes, the CNTFET modified by linker only had good response effect was found. Besides,after introduction of Escherichia coli O157：H7 at various concentrations caused a sharp increase in the source-drain resistance,and the resistance increased with the increase of the concentration of Escherichia coli O157：H7 solution, which indicated the possibility of CNTFET biosensor to detect Escherichia coil O157： H7.
作者 符晓龙 杨丹娜 谌志强 李赛
机构地区 四川大学化学与工程学院 中国人民解放军军事医学科学院
出处 《化工新型材料》 CAS CSCD 北大核心 2015年第8期192-194,共3页 New Chemical Materials
基金 国家自然科学基金资助项目(20805033) 教育部留学回国人员科研启动基金资助项目(2008890-19-9)
关键词 碳纳米管场效应晶体管 生物传感器 大肠杆菌 carbon-nanotube field-effect transistor biosensor Escherichia coli O157：H7
分类号 O613.71 [理学—无机化学] TB383.1 [一般工业技术—材料科学与工程]
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参考文献20

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化工新型材料
2015年 第8期

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