草鱼呼肠孤病毒研究进展

Research progress on grass carp reovirus

草鱼(Ctenopharyngodon idellus)是我国淡水养殖的主要品种,为四大家鱼之一,尤其在我国气候温暖的南方如长江、珠江水域养殖量极大。然而草鱼在幼苗阶段极易发病,其中威胁最大是草鱼出血病(grass carp hemorrhage),死亡率可高达90%以上。草鱼呼肠孤病毒(grass carp reovirus,GCRV)是草鱼出血病的主要病原,由于其高度传染性与致死性,对我国草鱼养殖业造成了极大的损失。近年来,关于草鱼呼肠孤病毒的研究逐步增多,并且出现了新基因型报道,引起了多方关注。对草鱼呼肠孤病毒的病原学、分子生物学、免疫原性、检测和综合防治等进行综述,并展望未来的研究方向,旨在对该病的防治和深入研究提供指导。

Grass carp （ Ctenopharyngodon idellus ） is one of the most popular commercial fish species in south China. However, the juvenile grass carp is very easy to attack. Grass carp hemorrhage is one of the most serious diseases of grass carp, causing more than 90% mortality and huge economic loss to the aquaculture industry. Grass carp reovirus （ GCRV ） is the causative agent of grass carp hemorrhage which is highly contagious and lethal. In recent years, the research on grass carp reovirus has gradually increased. In addition, the new genotype of this virus has been reported and caused extensive concern. This review summarized multiple aspects, such as etiology, molecular biology and immunogenicity of GCRV, for the control of grass carp hemorrhage.