期刊文献+

疏水性物质外膜通道蛋白及应用研究进展

Advances on hydrophobic outer-membrane transporters of Gram-negative bacteria and its appliance
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摘要 疏水性物质外膜通道蛋白是G-细菌特有的摄取胞外疏水性物质的通道,与G-细菌降解疏水性有机污染物密切相关。该文对已发现的两类疏水性通道蛋白进行了综述,重点概括了这两类通道蛋白的结构、运输底物和机理以及它们的应用。另外还展望了类似通道蛋白的鉴定以及利用此类通道蛋白构建全细胞催化系统在环境修复中的应用。 Hydrophobic outer - membrane transporters are specific parts of Gram - negative ( G - ) bacteria and play important roles in the degradation of toxic organic pollutants by G- bacteria. In this review, the structures, the substrate profiles, the trans- port mechanisms and appliance of two groups of OM transporters for hydrophobic substance were summarized. In addition, how to discover the new proteins of this group and use these proteins to construct the whole - cell biocatalyst system for environment remediation were discussed.
出处 《生物技术》 CAS CSCD 北大核心 2015年第4期397-402,共6页 Biotechnology
基金 国家973计划项目("环境中有毒污染物的微生物捕获与脱毒降解耦联机制" No.2012CB22307) 国家自然科学基金项目("污水生物处理" No.51422803 "金属还原菌和零价铁对多溴联苯醚的协同降解机理研究" No.21207019) 广州市珠江科技新星专项("持久性有机污染物PBDEs的生物-化学耦合脱毒机制和技术研究" 2014J2200076) 中国科学院农业与环境微生物学重点实验室开放研究基金项目("Shewanella decolorationis S12依赖TonB蛋白的受体在降解多溴联苯醚中的作用机制")资助
关键词 外膜通道蛋白 疏水性物质 蛋白结构 全细胞生物催化系统 环境修复 outer - membrane transporter, hydrophobic substances, protein structure, whole - cell biocatalyst system
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