小儿EB病毒感染200例临床病例报道

Clinical Case Report of 200 Cases of EB Virus Infection in Children

目的:探讨小儿EB病毒(EBV)感染的临床情况。方法:抽取本院接诊的小儿EB病毒感染患儿200例作为研究对象,根据急慢性分为两组,急性组120例、慢性组80例。两组均进行实验室检查,对比分析两组检查结果。结果:EB病毒感染患儿首发症状主要有发热、咳嗽、咽痛及淋巴结肿大等;对比分析急性组与慢性组实验室指标可知,急性组总T细胞、CD8+T细胞及CD8+T细胞/HLA-DR均显著高于慢性组(P<0.05)。结论:EB病毒感染患儿临床表现复杂,而且常累及多种系统,总T细胞、CD8+T细胞及CD8+T细胞/HLA-DR等可作为急性与慢性的判别标准,同时加强CD8+T细胞监测,对预后也有着积极的意义,应加强重视。

Objective： To investigate the clinical situation of EB virus （ EBV ） infection in children.Method ： 200 cases of EB virus infection from our hospital admissions were selected as the object of study, they were divided into two groups according to acute and chronic, 120 cases of acute, 80 cases of chronic.The two groups were carried out the laboratory examination, the results of the two groups were compared and analyzed. Result： Initial symptoms of Epstein Barr virus infection included fever, cough, sore throat and swollen lymph nodes. The total T cells, CD8^＋ T cells and CD8^＋ T cells/HLA-DR of acute group were significantly higher than those of chronic group （ P〈0.05 ） . Conclusion： Clinical manifestations of EB virus infection in children is complex and often involve a variety of systems, total T cells, CD8^＋ T cells and CD8^＋ T cells/HLA-DR can as acute and chronic comparision criterion, and strengthen monitoring of CD8^＋ T cells, also has a positive significance on the prognosis, should pay more attention.