糖尿病肾病与非糖尿病肾病贫血的对照研究

Control study of anemia on diabetic nephropathy and non-diabetic nephropathy

目的 探讨糖尿病肾病与非糖尿病肾病患者贫血的差异。方法 选取肾内科2010年1月~2015年1月收治的162例慢性肾病（CKD）患者,按病因分为糖尿病肾病组（n=70）及非糖尿病肾病组（n=92）,比较两组患者贫血发生率,贫血程度,血红蛋白（Hb）及红细胞计数（RBC）水平差异,比较两组间不同肾病分级（CKD1~CKD4）贫血发生率、RBC、Hb水平差异。结果 糖尿病肾病患者贫血发生率高于非糖尿病肾病患者,贫血严重程度与非糖尿病肾病组比较,差异有统计学意义（P〈0.05）,Hb及RBC水平低于非糖尿病肾病组。糖尿病肾病组CKD1~CKD4分级患者贫血发生率高于非糖尿病肾病组患者同级别CKD1~CKD4分级患者,RBC、Hb水平均低于非糖尿病肾病组患者同级别CKD1~CKD4分级患者。结论 糖尿病肾病患者更易发生贫血,且贫血程度较重,临床治疗时应给予充分重视。

Objective To investigate the difference of anemia degree on diabetic nephropathy and non-diabetic nephropathy. Methods 162 patients who was in hospital in nephrology department with nephropathy from January 2010 to January 2015 were selected and divided into diabetic nephropathy groups（n =70） and non-diabetic nephropathy groups（n=92） according to pathogeny,and incidence rate of anemia,anemia degree,level of Hb and RBC were contrasted between diabetic nephropathy groups and non-diabetic nephropathy groups,and incidence rate of anemia,anemia degree,level of Hb and RBC were contrasted in corresponding CKD grade between two groups. Results Incidence rate of anemia was higher in diabetic nephropathy groups than in non-diabetic nephropathy groups,anemia degree was different diabetic nephropathy groups and non-diabetic nephropathy groups,level of Hb and RBC were lower in diabetic nephropathy groups than in non-diabetic nephropathy groups,incidence rate of anemia was higher,and level of RBC and Hb was lower in each CKD degree（CKD1 to CKD4） of diabetic nephropathy than in corresponding CKD degree（CKD1to CKD4） of non-diabetic nephropathy. Conclusion Anemia is more common in diabetic nephropathy and serious in diabetic nephropathy,and anemia degree is more serious,that should be pay more attention.