重症胰腺炎患者应用血液净化治疗对于控制全身炎性反应综合征的效果研究

Application of blood purification therapy in patients with severe acute pancreatitis to treat systemic inflammatory response syndrome

目的:分析重症胰腺炎患者应用血液净化治疗对于控制全身炎性反应综合征的效果。方法:随机选取2013年4月—2014年4月于本院就诊的90例重症胰腺炎患者作为研究对象,并依据数字表法将其随机分为A组及B组,每组45例;A组患者进行间歇性血液净化,B组进行连续性血液净化。比较两组患者各项指标的检测结果。结果:B组患者血清肌酐、尿素氮、血清钠、血清氯等检测值均低于A组;B组患者白细胞介素-6、肿瘤坏死因子检测值均低于A组,P<0.05。结论:重症胰腺炎患者应用血液净化治疗对于控制全身炎性反应综合征效果良好,但相对于间歇性血液净化来说,连续性血液净化技术效果更佳,可有效改善全身炎性反应综合征,值得推广。

Objective： To analyze the effects of blood purification therapy for patients with severe acute pancreatitis（ SAP） in the control of systemic inflammatory response syndrome. Methods： 90 cases of SAP patients were randomly selected in 2013 April —2014 year in April in our hospital as the research object,and on the basis of the digital table method which were randomly divided into group A and group B,45 cases in each group; group A patients undergoing intermittent hemodialysis,B groups were treated with continuous blood purification. And then,the various indexes detected in both groups were compared. Results： The serum creatinine,blood urea nitrogen,serum sodium,serum chlorine were lower in group B than those in group A. Interleukin- 6,tumor necrosis factor were lower in group B than those in group A after treatment（ P〈 0. 05）. Conclusion： The effects of blood purification therapy on patients with severe acute pancreatitis to control systemic inflammatory response syndrome is good,and the continuous blood purification is better than intermittent hemodialysis. It can effectively improve the systemic inflammatory response syndrome and worthy of promotion.