摘要
近年来,对溶血栓药物的研究取得了较大进展。本文对包括尿激酶(urokinase,UK)、链激酶(streptokinase,SK)、组织型纤溶酶原激活剂(tissue type plasminogen activator,t PA)、葡激酶(straphylokinase,Sa K)、纳豆激酶(nattokinase,NK)、重组型纤溶酶原激活物在内的历代溶血栓药物的发展历程、基本性质、优缺点、溶血栓机制及发展方向作一综述。
In recent years, the research on thrombolytic drugs has made a great progress. This article describes the development process, basic properties, advantages and disadvantages, thrombolytic mechanisms and prospects of successive thrombolytic drugs, including urokinase(UK), streptokinase(SK), tissue type plasminogen activator(t PA), straphylokinase(Sa K), nattokinase(NK)and recombinant plasminogen activator.
出处
《中国生物制品学杂志》
CAS
CSCD
2015年第8期875-879,共5页
Chinese Journal of Biologicals
基金
华中科技大学大学生创新基金支持
关键词
血栓
溶血栓药
尿激酶
组织型纤溶酶原激活剂
重组型纤溶酶原激活物
Blood clots
Thrombolytic drugs
Urokinase(UK)
Tissue type plasminogen activator(t PA)
Recombinant plasminogen activator