脑梗死患者超敏C-反应蛋白、纤维蛋白原检测及临床意义

Detectionand and clinical significance of high sensitivity C reactive protein, fibrinogen in patients with cerebral infarction

目的 研究超敏C-反应蛋白（hs-CRP）、纤维蛋白原检测对脑梗死患者的临床意义.方法 以驻马店市中心医院2013年1月至2014年3月收治的100例脑梗死患者为研究对象,其中轻型30例,中型40例,重型30例,选择同期行健康体检的50例正常人群为对照组,通过乳胶比浊法、免疫比浊法分别对患者、健康人群hs-CRP、血浆纤维蛋白原（FIB）水平进行测定.结果 脑梗死组与对照组hs-CRP[（11.64±6.35） mg/LVS（5.10±3.17） mg/L]、FIB[（4.85±1.32） g/L VS（3.03±0.94）g/L]比较差异有统计学意义（P＜0.01）.另外,不同严重程度脑梗死患者hs-CRP、FIB比较差异有统计学意义（F值分别为17.84、13.50,P＜0.01）.结论 hs-CRP、FIB可作为脑梗死病情发生、严重程度评估的重要指标.

Objective To study the clinical significance of high-sensitivity C reactive protein （hs-cRP）,fibrinogen detection in patients with cerebral infarction.Methods One hundred cases of cerebral infarction were treated in our hospital from January 2013 to March 2014 as the study objects,including 30 cases of mild,medium in 40 cases,severe in 30 cases,normal people of 50 cases underwent physical examinationas as control group,with latex turbidimetry,immuneturbidimetry respectively measured patients and hs-CRP,plasma fibrinogen （FIB） levels.Results Between the cerebralinfarction group and control group,hs-CRP[（11.64 ±6.35） mg/L VS（5.10±3.17） mg/L],FIB[（4.85 ± 1.32） g/L VS（3.03 ± 0.94）g/L] had significant difference（P 〈0.01）.In addition,the severity of cerebral infarction and hs-CRP,FIB had difference between the two groups （F =17.84,13.50,P 〈 0.01）.Conclusions hs-CRP and FIB may be the important indexes for cerebral infarction disease occurrence and severity assessment.