痰热清注射液治疗慢性阻塞性肺疾病急性加重期

Effects of tanreqing injection on acute exacerbations of chronic obstructive pulmonary disease

目的 观察痰热清注射液治疗慢性阻塞性肺疾病急性加重期（AECOPD）的临床疗效.方法 选取郑州大学附属洛阳中心医院收治的AECOPD患者92例作为研究对象,随机将患者分为对照组和观察组,对照组行常规治疗,观察组在对照组基础上取痰热清注射液治疗,观察治疗前后白细胞计数、中性粒子细胞、C-反应蛋白（CRP）、肺功能指标等的变化,并评估临床疗效.结果 观察组治疗有效率为89.13％,显著高于对照组71.74％,差异具有统计学意义（P＜0.05）.观察组治疗后CRP为（10.16±3.21） mg/L显著低于对照组（17.20±4.51）mg/L,差异具有统计学意义（P＜0.05）.观察组1秒用力呼气容积（FEVl）、用力肺活量（FVC）、FEVl/FVC（FEVl％）分别为（1.62±0.60）L、（2.63±1.12）L、（63.26±9.84）％,显著高于对照组,差异具有统计学意义（P＜0.05）.结论 在常规治疗的基础上辅以痰热清注射液治疗AECOPD,能够改善患者肺功能,提高临床疗效.

Objective To observe the clinical curative effect of taureqing injection on acute exacerbation of chronic obstructive pulmonary disease （AECOPD）.Methods Ninety-two AECOPD patients admitted to the hospital as the research objects,they were randomly divided into observation group and control group,the control group received routine treatment,the observation group took Tanreqing injection on the basis of the control group,the changes of white blood cell count,neutrophil cells,C reactive protein,lung function indicators,and evaluation of clinical efficacy before and after treatment were observed.Results The effective rate of the observation group （89.13%） was significantly higher than that in the control group （71.74%）,there was significant difference （P 〈0.05）.The observation group after treatment,CRP [（10.16 ±3.21） mg/L] was significantly lower than that of control group [（17.20 ±4.51） mg/L],there was significant difference （P〈0.05）.In observation group,FEV1,FVC and FEV1/FVC were （1.62 ±0.60） L,（2.63 ± 1.12） L,（63.26 ± 9.84） %,which were significantly higher than those in control group,the differences were significant （P 〈 0.05）.Conclusions On the basis of conventional therapy,Tanreqing injection in treatment of AECOPD can improve pulmonary function,improve clinical curative effect.