亚临床甲状腺功能减退合并妊娠期糖尿病孕妇血清IL-17、IL-23的表达被引量：5

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摘要目的探讨亚临床甲状腺功能减退(SCH)合并妊娠期糖尿病(GDM)孕妇血清IL-17、IL-23的表达及其与TSH的相关性。方法选取检查诊断的SCH合并GDM孕妇63例作为观察组,同期健康体检孕妇50例为对照组,采用贝克曼DXI800化学发光分析仪检测TSH;ELISA法检测血清IL-17和IL-23,对结果进行分析比较。结果观察组孕妇组血清TSH为(6.48±2.73)m IU/L、IL-17为(49.82±20.06)pg/ml、IL-23为(56.61±22.44)pg/ml高于对照组的(1.89±0.91)m IU/L、(26.81±13.61)pg/ml、(27.78±12.89)pg/ml,差异有统计学意义(P<0.01);患者血清IL-17、IL-23与TSH呈正相关(P=0.002)。结论 IL-17、IL-23可能在SCH合并GDM的发病中起重要作用,可能成为SCH合并GDM早期诊断、治疗及预后判断的重要指标。

作者郑建霞靳颖刘殿卿刘娜

机构地区河北省唐山市妇幼保健院检验科

出处《中国妇幼保健》 CAS 2015年第25期4293-4295,共3页 Maternal and Child Health Care of China

关键词亚临床甲状腺功能减退妊娠期糖尿病白细胞介素-17 白细胞介素-23 促甲状腺素

分类号 R714.256 [医药卫生—妇产科学]

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