子宫肌瘤危险因素病例对照Logistic回归分析

Logistic regression on risk factors of uterine fibroids:a case-control study

目的通过病例对照Logistic回归分析探索子宫肌瘤发病的危险因素。方法以2014年3月~6月在吉林大学第一医院妇科门诊就诊的200例子宫肌瘤患者为病例组,同期在吉林大学第一医院就诊或健康体检的对象200例为对照组。进行病例对照Logistic回归分析探索子宫肌瘤发病危险因素。结果单因素分析结果显示：病例组与对照组民族、婚姻状态、年龄及体质指数（BMI）之间差异有统计学意义（P=0.003、P〈0.001、P〈0.001、P=0.035）,汉族、结过婚、年龄较大（40岁~）和BMI（18.5 kg/m2~）是子宫肌瘤的危险因素。经Logistic回归分析发现：病例组和对照组民族、婚姻状况和年龄之间差异有统计学意义（P=0.002、P=0.016、P〈0.001）,汉族、结过婚、年龄较大（40岁~）是子宫肌瘤发病的危险因素。结论针对危险因素采取预防措施是有效预防子宫肌瘤发生的手段。而女性本身需要调节好自己心身状态,加强锻炼,减少子宫肌瘤的发生。

Objective： To analyze and explore the risk factors of uterine fibroids through Logistic regression case-control study.Methods： Two hundred patients diagnosed as uterine fibroids in Gynecological Outpatient in the First Hospital of Jilin University from March to June in 2014 were selected as case group,two hundred women with normal uteri after healthy physical examination in the hospital during the same period were selected as control group. Logistic regression case-control study was conducted to analyze and explore the risk factors of uterine fibroids. Results： Univariate analysis showed that there were statistically significant differences in nationality,marital status,age,and body mass index（ BMI） between case group and control group（ P = 0. 003,P0. 001,P0. 001,P = 0. 035）; Han nationality,married status,age（ more than 40 years old）,and BMI（ 18. 5 kg / m2） were risk factors of uterine fibroids. Logistic regression analysis found there were statistically significant differences in nationality,marital status,and age between case group and control group（ P = 0. 002,P = 0. 016,P0. 001）; Han nationality,married status,age（ more than 40 years old）,and BMI（ 18. 5 kg / m2） were risk factors of uterine fibroids.Conclusion： Taking interventional measures targeting to the risk factors are effective methods to prevent uterine fibroids. The women should adjust psychological and physical states of themselves and strengthen excises to reduce the occurrence of uterine fibroids.