放置曼月乐治疗子宫腺肌病临床疗效观察

Observation of clinical effect by placement of mirena in the treatment of adenomyosis

目的探讨放置曼月乐(左炔诺孕酮宫内缓释系统,LNG-IUS)治疗子宫腺肌病的临床疗效。方法回顾性分析56例子宫腺肌病患者放置曼月乐的临床资料,比较放置曼月乐对月经量变化、痛经视觉模拟评分法(VAS)评分、子宫体积、内膜厚度及血红蛋白变化和不良反应的影响。结果放置曼月乐3个月后,子宫腺肌病患者月经量显著减少;痛经VAS评分显著降低;血红蛋白水平显著上升;子宫内膜厚度显著变薄;子宫体积在放置12个月后显著减少,差异均具有统计学意义(P<0.05或P<0.01)。结论放置曼月乐治疗子宫腺肌病可以有效缓解患者痛经、减少月经量及改善贫血,是一种安全有效、值得推广的治疗方法。

ObjectiveTo investigate clinical effect by placement of mirena （levonorgestrel-releasing intrauterine system, LNG-IUS） in the treatment of adenomyosis.MethodsClinical data of 56 adenomyosis patients receiving mirena were retrospectively analyzed. Comparisons were made on influences by mirena on menstrual blood volume, dysmenorrhea visual analogue scale （VAS） score, uterine volume, endometrial thickness, hemoglobin, and adverse reactions.ResultsAfter placement of mirena for 3 months, these adenomyosis patients had obviously reduced menstrual blood volume, VAS score, endometrial thickness, and increased hemoglobin level. After placement for 12 months, uterine volume was remarkably decreased. The differences all had statistical significance （P〈0.05 orP〈0.01）.ConclusionPlacement of mirena can effectively relieve dysmenorrheal, reduce menstrual blood volume, and improve anemia. It is a safe and effective treatment method which is worthy of promotion.