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急性心肌梗死早期糖尿病与非糖尿病者血脂水平

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摘要 目的探讨糖尿病及非糖尿病患者急性心肌梗死早期血脂水平变化。方法回顾性分析336例急性心肌梗死患者的临床资料,根据是否合并糖尿病分为糖尿病组94例,非糖尿病组242例。比较两组血脂水平。结果糖尿病组载脂蛋白A(Apo-A)(1.0±0.2)g/L,非糖尿病组Apo-A(1.3±0.3)g/L,糖尿病组Apo-A显著低于非糖尿病组(P<0.05)。两组左主干支、左前降支、左回旋支、右冠状动脉支狭窄积分差异无统计学意义(P>0.05)。结论糖尿病患者Apo-A水平低于非糖尿病患者。两组患者白细胞水平均显著升高提示急性心肌梗死患者在急性期存在炎症反应,这可能与患者甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)水平下降有关。
出处 《中国实用医药》 2015年第21期51-52,共2页 China Practical Medicine
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  • 1苏钦峰,赵玉兰.2型糖尿病患者纤溶系统的变化与大血管病变的相关性研究[J].医药论坛杂志,2007,28(11):34-36. 被引量:6
  • 2Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)[J].Lancet,1994,344:1383 -1389.
  • 3Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of ini tial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group[J]. N Engl J Med,1998,339:1349-1357.
  • 4Downs J R, Clearfield M, Weis S, Whitney E, Shapiro D R, Beere P A, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study[J]. JAMA, 1998,279: 1615- 1622.
  • 5Nakamura H, Arakawa K, Itakura H, Kitabatake A, Goto Y, Toyota T, et al. Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study); a prospective randomised controlled trial[J]. Lancet, 2006,368 :1155-1163.
  • 6Cannon C, Braunwald E, MeCabe C, Rader D, Rouleau J, Belder R,et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes [J]. New Engl J Med, 2004, 350:1495 -1504.
  • 7Waters D,Guyton J, Herrington D, McGowan M, Wenger N, Shear C. Treating to New Targets (TNT) Study: does lowering low-density lipoprotein cholesterol levels below currently recommended guidelines yield incremental clinical benefit[J]?Am J Cardiol,2004,93:154-158.
  • 8Gordon T, Castelli W P, Hjortland M C, Kannel W B, Dawber T R. High density lipoprotein as a protective factor against coro nary heart disease: The Framingham study[J]. Am J Med, 1977,62:707- 714.
  • 9Miller N E, Thelle D S, Forde O H, Mjos O D. The Troms: heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study[J]. Lancet, 1977,309: 965 -968.
  • 10Barter P, Gotto A M, LaRosa J C, Maroni J, Szarek M, Grundy S M, et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events[J]. New Engl J Med, 2007,357: 1301- 1310.

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