摘要
考察了HZl6c型大孔吸附树脂对3-甲基黄嘌呤粗粉的纯化工艺。利用吸附及解吸的单因素影响试验,筛选树脂的最佳工艺条件。最佳纯化工艺条件为:HZl6c型大孔吸附树脂静态吸附量为22.5mg/g;上样液3-甲基黄嘌呤pH为9.5~10.0;解吸溶剂为60%乙醇溶液(pH10.0),控制解吸速度为2.0mL/min,解吸体积约为3倍树脂体积(3BV)。该3-甲基黄嘌呤的纯化工艺路线收率达到75%。大孔吸附树脂HZl6c能有效纯化3-甲基黄嘌呤,该工艺简捷,有一定工业化应用价值。
The purification process of 3-methylxanthine by HZ16c nmcroporous resin is studied. The optimal purification conditions of resin are obtained based on adsorption and desorption. The key optimum conditions are : about 22.5 mg/g of the static adsorption capacities of HZ16e resin for 3-methylxanthine, 60% alcohol ( pH 10.0 ) as the elution ,2. 0 mL/min of eluting velocity and about 3 BV of elution volume. The average yield of purification process of 3- methylxanthine reaches 75%. HZ16c resin is an ideal macroporous adsorbent for separating and purifying 3- methylxanthine. This purification process could be used in industrial production.
出处
《现代化工》
CAS
CSCD
北大核心
2015年第8期121-123,125,共4页
Modern Chemical Industry
基金
河北省高等学校科学研究青年基金项目(QN20131108)
关键词
3-甲基黄嘌呤
大孔吸附树脂
纯化
工艺
3-methylxanthine
macroporous adsorption resin
purification
process