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陀螺刀治疗老年人早期肺癌效果分析 被引量:3

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摘要 目的:评价全身陀螺旋转式60Co立体定向放射外科治疗系统(陀螺刀)对老年人早期肺癌的近期疗效和放射反应。方法对35例70岁以上的ⅠA、ⅠB、ⅡA期非小细胞肺癌(NSCLC)采用陀螺刀治疗。照射剂量肿瘤边缘(50%剂量线)7 Gy/次,治疗8次,5次/周,肿瘤周边物理剂量56 Gy。结果35例均顺利完成治疗计划,与治疗后2~3个月影像资料进行比对,病灶完全缓解(CR)率57.1%(20/35),部分缓解(PR)率42.9%(15/35),总有效率100%。1年肿瘤局控率94.3%(33/35),1年总生存率88.6%(31/35),2年肿瘤局控率74.3%(26/35),2年总生存率71.4%(25/35)。Ⅰ、Ⅱ级放射性肺炎发生率22.9%(8/35),Ⅰ、Ⅱ级放射性食管炎发生率11.4%(4/35),无Ⅲ级以上放射性反应。结论陀螺刀对早期老年人NSCLC近期疗效好,治疗不良反应轻微,是老年人早期肺癌的一种安全有效的局部治疗手段。
出处 《肿瘤研究与临床》 CAS 2015年第7期480-482,共3页 Cancer Research and Clinic
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