妊娠期糖尿病患者早期心肌损害的监测

Monitoring of early myocardial damage in patients with gestational diabetes

目的探讨检测血清N末端B型钠尿肽原(NT-pro BNP)和心脏型脂肪酸结合蛋白(h-FABP)水平对妊娠期糖尿病(GDM)患者早期心肌损害的监测价值。方法选择我院住院和门诊临床确诊的GDM患者120例,并选择同期正常妊娠期妇女120例作为对照组。检测各组血清中NT-pro BNP和h-FABP水平,并进行对比分析。结果 GDM患者血清NT-pro BNP和h-FABP水平高于对照组,差异有统计学意义(P<0.01)。结论联合检测血清NT-pro BNP及h-FABP水平可及时了解GDM患者早期心肌细胞损害及心脏功能情况,对指导治疗及改善预后具有重要意义。

Objective：Explore to detect serum N end of b-type natriuretic peptide（NT-pro BNP）and heart type fatty acid binding protein（h-FABP）levels in patients with gestational diabetes mellitus（GDM）monitoring value of early myocardial damage. Methods：Choose our hospital inpatient and outpatient clinical diagnosis of GDM patients 120 cases,the same period and select normal pregnancy women 120 cases as control group. Testing each NT-pro BNP in serum and h-FABP level,and comparison analysis. Results：GDM patients serum NT-pro BNP and h-FABP level higher than the control group,the difference was statistically significant（P〈0. 01）. Conclusion：Combined detection of serum level of NT-pro BNP and h-FABP can timely understand the GDM patients with early myocardial cell damage and cardiac function,is of great significance to guide treatment and improve prognosis.