利用激光散斑成像技术观察2型糖尿病合并动脉硬化症患者舌象微循环变化的临床研究

Tongue microcirculation changes in type 2 diabetic patients with atherosclerosis

目的应用激光散斑成像技术研究2型糖尿病合并动脉硬化症患者的舌象微循环变化。方法随机抽取2014年4月至2014年7月在辽宁中医药大学附属医院内分泌科住院的单纯2型糖尿病及2型糖尿病合并动脉硬化症患者,应用MOOR FLPI2变焦激光散斑血流实时成像系统,针对受试者舌尖、舌根及舌的左右两侧四个位置,分别测量记录其舌体血流量,舌体血流面积,然后进行统计分析,以探讨单纯2型糖尿病患者及2型糖尿病合并动脉硬化症患者舌象微循环的异同。结果单纯2型糖尿病患者的舌面不同区域血流量的平均值及血流面积的平均值均明显高于2型糖尿病合并动脉硬化症患者,差异有显著性(P<0.05)。结论 2型糖尿病合并动脉硬化症患者存在微循环障碍。微循环障碍在糖尿病大血管并发症的发生、发展过程中起着极其重要的作用。

Objective To study the tongue microcirculation changes of type 2 diabetic patients with atherosclero-sis. Methods April 2014 to July 2014 in Liaoning university of traditional Chinese medicine affiliated hospital endocrinology of simple type 2 diabetes patients and patients with type 2 diabetes mellitus with atherosclerosis,application of MOOR FLPI2 real-time blood flow to zoom laser speckle imaging system,selection of subjects to the tip of the tongue,and your tongue and the tongue of left and right sides of the four locations,measured record its tongue body blood flow,blood flow to the tongue body area,statistical analysis,and then to discuss type 2 diabetes mellitus patients and patients with type 2 diabetes mellitus with atherosclerosis tongue microcirculation of the similarities and differences. Results the lingual surfaces of pure in pa-tients with type 2 diabetes and blood flow area of the average of blood flow in different regions of the average were significantly higher than that of patients with type 2 diabetes mellitus with atherosclerosis,the difference was statistically significant （ P〈0. 05 ） . Conclusion in patients with type2 diabetes mellitus with atherosclerosis is microcirculation dysfunc-tion. Microcirculation in the occurrence and development of diabetic vascular complications plays an extremely important role in the process.