摘要
A direct C–H amination reaction of N-Ts-2-Styrylaniline derivatives to realize the synthesis of indole derivatives was developed in the presence of copper salt. A variety of N-Ts-2-Styrylaniline derivatives were transformed into the corresponding indole products in good to excellent yield under mild conditions with the oxidation of potassium persulfate.
A direct C–H amination reaction of N-Ts-2-Styrylaniline derivatives to realize the synthesis of indole derivatives was developed in the presence of copper salt. A variety of N-Ts-2-Styrylaniline derivatives were transformed into the corresponding indole products in good to excellent yield under mild conditions with the oxidation of potassium persulfate.
基金
financially supported by the National Natural Science Foundation of China(Nos.21272169,21302135)
the Key Innovation Team of Science & Technology in Zhejiang Province(No.2010R50018-10)
the Science and Technology Bureau of Taizhou(No.08KY10)
the Key Disciplines of Applied Chemistry of Zhejiang Province,Taizhou University
