直肠癌患者脉管内癌栓与临床病理因素及预后的关系

The Relationship of Rectal Carcinoma Patient＇s Intra-angiologia Cancer-embolus with Clinical Pathological Factors and Prognosis

为探讨直肠癌患者脉管内癌栓与临床病理因素的关系及其对疾病预后的影响，回顾分析2007年1月至2009年12月我科行手术治疗的382例直肠癌患者的临床及病理资料，分析脉管内癌栓与肿瘤浸润深度、组织分化程度、淋巴结转移程度的关系，并比较脉管内癌栓阳性组和阴性组患者术后3年、5年生存率的差异。结果显示，382例患者中，脉管内癌栓阳性56例。直肠癌患者脉管内癌栓的存在与肿瘤浸润深度、组织分化程度、淋巴结转移程度有关，P〈0．05；与性别、年龄无关，P〉0．05。脉管内癌栓阳性组患者术后3年、5年生存率明显低于脉管内癌栓阴性组，P〈0．05。结果表明，脉管内癌栓是直肠癌患者非常重要的预后因素，应给予高度关注。

In order to explore the relationship of rectal carcinoma patient＇s intra-angiologia cancer-embolus with clinical pathological factors,and its influence on prognosis of disease,authors retrospectively analyzed the clinical and pathological data of 382 cases who had received surgery from 2007-01 to 2009-12,investigated the relationship of intra-angiologia cancer-embolus with neoplasm infiltration depth, tissue differentiation degree,and lymph node metastasis, and compared the differences postoperation of 3-year, 5-year survival rate between cancer-embolus positivity group and cancer-embolus negativity group.As results,in 382 cases 56 were cancer-embolus positive; rectal carcinoma patient＇s existing intra-angiologia cancer-embolus was related to their neoplasm infiltration depth, tissue differentiation degree, and metastasis degree of lymph node（ P〈0.05） ,but not to sex and age（ P〉0.05） ~postoperation 3-year and 5-year survival rate of cancer-embolus positivity group was significantly lower than that of cancer-embolus negativity group（ P〈0.05）.Results show that intra-angiologia cancer-embolus is an important factor related to the prognosis of patients with rectal carcinoma, which should be noticed.