祛风活络泄浊汤治疗痰浊阻滞型慢性痛风性关节炎的临床观察

Clinical Observation on the Treatment of Chronic Gouty Arthritis of Feng Shi Yu Zu Zheng by Qu Feng Huo Luo Xie Zhuo Tang

[目的]观察祛风活络泄浊汤治疗痰浊阻滞型慢性痛风性关节炎的临床疗效。[方法]选择2013年6月至2014年12月在乐清市第二人民医院门诊的116例痰浊阻滞型慢性痛风性关节炎患者,通过随机数字表法平均分为治疗组和对照组,治疗组58例予自拟祛风活络泄浊汤治疗,对照组58例予别嘌醇治疗,疗程均为2个月。评估两组患者治疗前、治疗2个月后的血尿酸(BUA)值及临床疗效,并进行适当统计分析。[结果]治疗前两组BUA值无明显差异;治疗2个月后,治疗组BUA值低于对照组,且两组差异有统计学意义(P<0.05)。治疗组总有效率为87.9%,对照组总有效率为68.9%,治疗组的疗效优于对照组的疗效,且两组差异有统计学意义(P<0.05)。[结论]祛风活络泄浊汤治疗痰浊阻滞型慢性痛风性关节炎有较好的临床效果,且优于常规西医别嘌醇的疗效,值得临床进一步观察研究。

[Objective] To observe the clinical efficacy of using Qu Feng Hun Luo Xie Zhuo tang to treat the chronic gouty arthritis of Tan Zhuo Zu Zhi Zheng.[Metheds] From June 2013 to December 2014, 116 patients who got chronic gouty arthritis of Tan Zhuo Zu Zhi Zheng were chosen from the orthopedic outpatient cases in our hospital. All patients were equally divided into treatment group and control group by using random number table. The 58 patients of treatment group were treated with Qu Fang Huo Luo Xie Zhuo tang while the other 58 patients of the control group were treated with allopurino for 2 months. We analyzed the value of the Blood Uric Acid（BUA） and clinical efficacy before treatment and 2 months after treatment.[Results] The results showed that value of the BUA of two groups had no significant difference（P〉0.05） before treatment, after 2 months, the value of the BUA of treatment group was lower than control group, the value of the BUA of two groups had significant difference（P〈O.05）.The rate of effective cases in treatment group was 87.9% while the control group was 68.9%, the clinical efficacy of the treatment group was better than the control group.There was statistical difference in the results of treatment between the greups（P〈0.05）.[Conclusion] Using Qu Fang Huo Luo Xie Zhuo tang to treat the chronic gouty arthritis of Tan Zhuo Zu Zhi Zbeng could get good effect,and it was better than allopurinol which was often used in western medicine.It was worth to be researched and observed in clinic.