48例高危妊娠产后出血产妇应用卡前列素氨丁三醇治疗的效果研究

Effects of carboprost tromethamine treatment application in 48 cases of high-risk pregnancy maternal postpartum hemorrhage

目的研究48例高危妊娠产后出血产妇应用卡前列素氨丁三醇治疗的产后出血量及效果。方法选择2013年4月至2014年7月我院收治的48例高危妊娠产后出血产妇,按照患者的入院顺序分为观察组(24例)和对照组(24例)。当胎儿出生之后,对所有患者加入500 ml的缩宫素20 U,配置0.9%生理盐水并对患者进行静脉注射,观察组患者在此基础上给予250μg的卡前列素氨丁三醇进行注射。对两组患者在产后2 h以及24 h的出血量和产后出血发生的情况进行对比分析,对两组患者的疗效进行判定。结果观察组产妇在产后2 h的出血量(121.03±16.42)ml以及24 h的出血量(263.71±58.02)ml显然低于对照组,差异具有统计学意义(P<0.05)。观察组产妇产后出血率(8.33%)显然低于对照组(33.33%),两组间比较差异具有统计学意义(P<0.05)。观察组患者总的有效率显著高于对照组,差异具有统计学意义(P<0.05)。结论高危妊娠产后出血产妇应用卡前列素氨丁三醇治疗之后,可以有效的预防产后出血,减少产后的出血量,其效果良好,值得广泛推广使用。

Objective To investigate 48 cases of high-risk pregnancy maternal postpartum hemorrhage application Carboprost tromethamine treatment of postpartum hemorrhage and effect. Methods April 2013 to July 2014 in our hospital 48 cases of high-risk pregnancy maternal postpartum hemorrhage,according to the order of the patient＇s admission into the observation group（ 24 cases） and control group（ 24 cases）. After the birth,all patients adding 500 m L of oxytocin 20 U,Configuration 0. 9% saline intravenously and patients in the observation group were treated Carboprost 250 ug of tromethamine injection on this basis. Two groups of patients in the postpartum bleeding 24 h 2h and the amount and circumstances of postpartum hemorrhage occurred in a comparative analysis of the efficacy of the two groups were judged. Results The mothers in the postpartum hemorrhage 2h of（ 121. 03 ± 16. 42） ml of blood loss and 24h（ 263. 71 ± 58. 02） ml obviously lower than the control group,the difference was statistically significant（ P〈0. 05）. Observation group postpartum hemorrhage rate（ 8. 33%） was clearly lower than the control group（ 33. 33%）,the difference between the two groups was statistically significant（ P〈0. 05）. The total observation group were significantly higher response rate,the difference was statistically significant（ P〈0. 05）. Conclusions The high-risk pregnancy maternal postpartum hemorrhage after using Carboprost tromethamine,can effectively prevent postpartum hemorrhage,reduce the amount of bleeding after childbirth,the effect is good,worthy widely used.