1225例HIV/AIDS患者流行病学特征分析

Epidemiological Characteristics of 1324 HIV/AIDS Patients

目的:了解来陕西地区就诊的人类免疫缺陷病毒/艾滋病(Human immunodeficiency virus/Acquired immuno deficiency syndrome,HIV/AIDS)患者感染状况、流行特征。方法:收集来我院就诊的HIV/AIDS患者的基本信息,对其流行病学资料统计分析。结果:在调查的1225例HIV/AIDS患者中,男性占83.51%,平均年龄为(35.55±11.61)岁,50.98%为农民,小学及以下学历占33.55%,经血液途径感染250例,经性传播途径感染916例,其中同性性传播337例,经母婴垂直传播16例,就诊时CD4+T淋巴细胞计数平均值为(222.82±190.49)个/μL,56%的HIV/AIDS患者采用的抗病毒方案为齐多夫定(Zidovudine,AZT)/替诺福韦(Tenofovir Disoproxil Fumarate,TDF)+拉米夫定(Lamivudine,3TC)+依非韦伦(Efavirenz,EFV)方案。结论:陕西地区HIV/AIDS感染人数呈上升趋势,且年轻化加剧,同性性传播比例大幅增加。虽然治疗较为及时,应进一步在高危人群中积极宣传防艾知识与措施。

Objective： To understand the infection status and epidemiological characteristics of HIV/AIDS patients in Shaanxi province. Methods： The basic information of HIV/AIDS patients were collected in our clinic, and to analyze the epidemiological characteristics. Results： In the investigation of 1225 cases of H1V/AIDS infections, 83.51% were male, and the average age was （35.55± 11.61） years old, 50.98% were farmers, and 33.55% of the patients＇ education background were primary schooling or lower. 250 patients were infected through blood-borne transmission, 916 patients were infected by sexual transmission, of whom 337 patients were transmintted by homosexual behaviors, 16 patients were infected by vertical transmission. The average value of baseline CD4＋T cell count was （222.82 ± 190.49） cell/μL. 56% anti-retroviral therapeutic regimen was AZT/TDF＋3TC＋EFV. Conclusions： In Shaanxi province, the population of HIV/AIDS was on the increase and younger intensified. The proportion of homosexual transmission was higher. Although the treatment was in time, knowledge and methods of prevention should be disseminated in high-risk population.