脑梗死急性期血压变化特点及其与进展性脑梗死的关系

Characteristics of blood pressure in acute phase of cerebral infarction and its relation with progressive ischemic stroke

目的观察脑梗死急性期血压变化特点，探讨其与进展性脑梗死的关系。方法收集2013年7月-2014年4月本院收治的急性脑梗死患者129例。采用斯堪地那维亚卒中量表（Standinavian Stroke Scale，SSS）评估病情是否发生进展，监测患者发病后72h内的血压，分析血压变化特点及其与进展性脑梗死的关系。结果脑梗死发病72h内血压呈逐渐降低趋势。进展组患者高血压病史患病率显著高于非进展组，且各时段平均血压也显著高于非进展组。无高血压病史的患者各时段平均血压进展组显著高于非进展组，而有高血压病史的患者各时段平均血压2组比较无显著差异。结论脑梗死急性期血压呈自发性下降。对于无高血压病史的患者急性期血压增高与进展性脑梗死有关，而对有高血压病史的患者急性期血压增高或许有保护作用。

Objective To observe the characteristics of blood pressure in acute phase of cerebral infarction and investigate its relationship with progressive ischemic stroke. Methods This study collected 129 cases of hospitalized patients with acute cerebral infarction in Lianyungang Hospital of Traditional Chinese Medicine from July 2013 to April 2014. The patients were investigated by Scandinavian Stroke Scale to evaluate whether the ischemic stroke is progressive. Their blood pressures within 72 hours after onset were recorded. The characteristics of the blood pressure and its relationship with progressive ischemic stroke were analyzed. Results The blood pressures within 72 hours after onset declined spontaneously. The hypertension prevalence rate of progressive group was significantly higher than control group, and the average blood pressure was also significantly higher than control group. To the patients without hypertension, the average blood pressure of progressive group was significantly higher than control group. However, there was no significant difference between the average blood pressure of progressive group and control group with history of hypertension. Conclusions The blood pressure of cerebral infarction declined spontaneously in acute phase. To the patients without history of hypertension, increased blood pressure in acute phase is associated with progressive ischemic stroke. And to the patients with history of hypertension, increased blood pressure in acute phase may have orotective effect.