摘要
采用正反相硅胶,Sephadex LH-20,MCI树脂等常规柱色谱及高效液相色谱技术对中药木蝴蝶种子80%甲醇提取物进行化学成分的分离纯化,从中分离得到11个化合物,根据其理化性质以及核磁波谱数据鉴定化合物结构为木蝴蝶苷B(1)、白杨黄素(2)、黄苓苷元(3)、5,6-二羟基-7-甲氧基黄酮(4)、槲皮素-3-O-β-D-半乳糖苷(5)、槲皮素-7-O-β-D-葡萄糖苷(6)、2α,3β-二羟基羽扇豆醇(7)、羽扇豆醇(8)、顺式-连翘环己醇(9)、β-谷甾醇(10)、豆甾醇(11)。其中,化合物5为首次从木蝴蝶中分离得到。
Oroxylum indicum was a traditional Chinese medicine. In order to study the chemical constituents from the seed of O. indicum,the chemical constituents of 80% methanol extract of seeds of O. indicum were subjected to chromatography on silica gel,Sephadex LH-20,and preparative HPLC,leading to the isolation of eleven compounds. The structures were identified by various spectroscopic data including ESI-MS,1H-NMR and13C-NMR data as oroxin B( 1),chrysin( 2),baicalein( 3),neglectein( 4),quercetin-3-O-β-D-galactopy ranoside( 5),quercetin-7-O-β-D-glucopyranoside( 6),2α,3β-dihydroxyllu Peol( 7),lupeol( 8),rengyol( 9),β-sitostero( 10),and stigmasterol( 11). Among them,compound 5 were firstly obtained from O. indicum.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2015年第15期3013-3016,共4页
China Journal of Chinese Materia Medica
关键词
木蝴蝶
提取分离
结构鉴定
化学成分
Oroxylum indicum
extraction and isolation
structure determination
chemical constituents