香砂平胃汤联合泮托拉唑对脑卒中后胃肠功能障碍疗效观察

Effective observation on treating gastrointestinal dysfunction following cerebral apoplexy with the Xiangsha Pingwei decoction plus pantoprazole

目的:观察香砂平胃汤联合泮托拉唑治疗脑卒中后胃肠功能障碍的临床疗效。方法:随机将100例患者分为观察组和对照组各50例。所有的患者均给予脑血管病的常规治疗,对照组采用泮托拉唑对症治疗;观察组在泮托拉唑治疗基础上合用香砂平胃汤辨证治疗,治疗2周为1个疗程,治疗前和治疗2周后进行疗效评定。结果:两组患者NIHSS评分均较治疗前有明显降低(P<0.01),观察组显著优于对照组(P<0.05);治疗后两组患者的疗效均较治疗前有明显提高,观察组明显优于对照组(P<0.05)。结论:香砂平胃汤联合泮托拉唑辨证治疗脑卒中后胃肠功能障碍疗效优于单纯西药治疗,并能改善患者的神经动能缺损程度,降低病死率,减少并发症。

Objective： To observe clinical efficacy of the Xiangsha Pingwei decoction plus pantoprazole on gastrointestinal dysfunction following cerebral apoplexy. Methods： 100 patients were randomly divided into the observed group and the control group, 50 cases for each. All patients were given conventional treatment of cerebrovascular disease. The control group was given symptomatic treatment with pantoprazole; the observed group was given the conventional treatment plus the Xiangsha Pingwei decoction, 2 weeks as a course. Before and after treatment, efficacies were assessed. Results： After treatment, NIHSS scores in two groups were decreased obviously （P〈0.01）; the efficacy in two groups were increased; and the observed group was better than the control group （P〈0.05）. Conclusion： The Xiangsha Pingwei decoction plus pantoprazole on gastrointestinal dysfunction following cerebral apoplexy shows a good efficacy, better than western medicine treatment simply, could improve the nerve defect level, with less mortality and complications.