奥拉西坦联合莫尼同治疗血管性痴呆36例的疗效观察

Efficacy of oxiracetam combined with nimodipine in the treatment of 36 cases with vascular dementia

目的:探究和分析奥拉西坦联合尼莫同治疗血管性痴呆的临床效果.方法:选择我院2014-02/2015-02收治的血管性痴呆患者72例为研究对象,随机分成对照组和实验组,各36例.对照组单用尼莫同进行治疗,实验组联合奥拉西坦以及尼莫同进行治疗.观察和比较两组患者的治疗效果.结果:在总有效率比较上,实验组比对照组高,差异明显,提示有统计学意义(p<0.05);在简易智力状态量表分值以及日常生活活动能力量表评分改善情况比较上,实验组优于对照组,差异明显,提示有统计学意义(P<0.05).结论:采用奥拉西坦联合尼莫同对血管性痴呆患者进行治疗,治疗效果理想,且对患者的预后改善理想,值得普及.

AIM： To investigate and analyze clinical effect of oxiracetam combined with nimodipine in the treatment of vascular dementia. METHODS： 72 cases with vascular dementia admitted in our hospital from February 2014 to February 2015 were ran- domly divided into control group and experimental group, with 36 cases in each. Control group was treated with nimodipine treat- ment, while the experimental group combined with oxiracetam and Nimotop in the treatment of vascular dementia. Observing and comparing two groups＇ outcomes. RESULTS： In the total effi- ciency comparison, the experimental group is higher than control group, with significant difference, P 〈 0.05, which has statistical significance ; and in the comparison of mini mental state examina- tion scores and activities of daily living scale scores, the experimental group was better than the control group, with significant difference, P 〈 0.05, which indicates a statistically significant. CONCLUSION： Combining with oxiraeetam and nimodipine in the treatment of vascular dementia has significant and ideal effect, and it is beneficial to the improvement of patients＇ prognosis, which is worth of promotion.