集束化干预控制MRSA感染与定植的效果观察

The effect of cluster-based intervention in the control of MRSA colonization and infection

目的通过采取集束化干预措施,长期、持续地对急诊重症监护病房(EICU)耐甲氧西林金黄色葡萄球菌(MRSA)感染与定植患者进行干预,并通过日常监测MRSA感染与定植状况以验证干预效果。方法 2014年1月至12月采用前瞻性调查方法对浙江省台州医院EICU住院的MRSA感染与定植患者进行集束化干预措施;对2012年1月至2013年12月的EICU出院患者进行回顾性调查;分析EICU住院患者采取集束化干预措施产生的效果。结果通过采取集束化干预措施,EICU住院患者发生MRSA感染与定植率明显下降,从2.79%下降至1.01%(P<0.01)。结论通过采取集束化干预措施可有效降低MRSA感染与定植率,从而阻断MRSA在医院内的传播。

Objective To control persistently the methicillin-resistant Staphylococcus aureus（MRSA）colonization and infection in emergency intensive care unit（EICU）patients using the cluster of intervention,and verify the effect of intervention by routine monitoring.Methods A prospective investigation was conducted to proceed the cluster-based intervention among EICU patients with MRSA colonization and infection in2014.A retrospective investigation was conducted among EICU patients who were discharged in 2012and2013.The effect of the cluster-based intervention was analyzed.Results The percentage of MRSA colonization and infection in EICU patients was obviously decreased from 2.79%to 1.01%（P〈0.01）by using the cluster-based intervention.Conclusion The cluster-based intervention can decrease the percentage of MRSA colonization and infection,and help to prevent the prevalence of MRSA in the hospital.