动态血糖监测系统在GDM治疗中对低血糖监测的应用

Application of Continuous Glucose Monitoring System in the Assessment of Hypoglycemia in GDM Patients

目的:研究动态血糖监测系统在妊娠期糖尿病(GDM)患者治疗中低血糖反应的准确性。方法:纳入2010年至2012年在我院住院的162例GDM患者,经饮食运动及胰岛素治疗后血糖控制达标后,随机分为两组,观察组予动态血糖监测系统(CGMS)监测血糖,对照组以手测血糖值(7次/d)3 d,比较分析两种检测方法中低血糖的发生率。结果:对于治疗后血糖达标患者,两者检测方法对空腹及餐后2 h血糖的测定比较,差异无统计学意义(P>0.05),而观察组监测出低血糖发生率为41.0%明显高于对照组的23.8%(P<0.05);其夜间低血糖发生率高。结论:CGMS能全面的反应GDM患者的血糖情况,能发现临床不易发现的低血糖,对GDM的治疗有指导作用。

Objective To explore the effect of hypoglycemia event report by continuous glucose monitoring system（CGMS） in gestational diabetes mellitus（GDM） patients treated with insulin. Methods A total of 162 GDM patients treated with insulin,as adjunct to diet and exercise were enrolled. All patients were randomized 1：1 to SMBG group and CGMS group and observed for 72 hours. All the indexes were compared between the fi rst day and the third day. Results There were no signifi cantly different in fasting plasma glucose（FPG） and two-hour postprandial plasma glucose（PPG） in both groups. Rates of hypoglycaemia event report is signifi cantly superior in CGMS group（P〈0.05）. Conclusion CGMS iss more effi cacious for detecting hypoglycemia, especially nocturnal hypoglycemia than SMBG.